Adjuvant treatment or primary topical monotherapy for ocular surface squamous neoplasia: a systematic review

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Adjuvant treatment or primary topical monotherapy for ocular surface squamous neoplasia: a systematic review.

In this systematic review, we evaluated studies involving adjuvant and primary topical treatment for ocular surface squamous neoplasia (OSSN). The findings were: (i) adjuvant 5-fluorouracil (5-FU) reduces the risk of relapse after surgical excision with mild side effects [level Ib, grade of recommendation (GR) A]. (ii) Primary topical mitomycin (MMC) produces a high rate of complete response, l...

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topical mitomycin c for partially excised ocular surface squamous neoplasia

purpose : to develop a guideline for the treatment of incompletely removed histopathologically documented ocular surface neoplasia (ossn) with mitomycin c (mmc). materials & methods : through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ossn were treated according to a protocol using 2-3 alternate 7-day courses of mmc 0.04%. clinical recurrence was r...

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Ocular Surface Squamous Neoplasia

The ocular surface is composed of the conjunctiva and the cornea. The conjunctiva is a mucous membrane which covers the globe and inner part of the eyelids. The morphology of conjunctival epithelial cells are nonkeratinized stratified epithelia which vary from cuboidal over the tarsus, to columnar in the fornices, to squamous epithelia on the globe. Goblet cells account for up to 10% of the bas...

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Ocular surface squamous neoplasia treated with topical interferon α 2b.

To cite: Pujari A. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218344 DESCRIPTION A 64-year-old male patient presented with fleshy lesion over the right temporal conjunctiva for the past 3 months with a gradual increase in size. History of trauma and pain was absent, and past history did not reveal any significant ocular/systemic morbidities. Right eye exa...

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Topical mitomycin-C for treatment of partially-excised ocular surface squamous neoplasia.

BACKGROUND This study was conducted to determine the treatment outcome of incompletely removed, histopathologically documented ocular surface squamous neoplasia with mitomycin-C. METHODS Through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ocular surface squamous neoplasia were treated according to a protocol using two to three alternate seven-day ...

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ژورنال

عنوان ژورنال: Arquivos Brasileiros de Oftalmologia

سال: 2017

ISSN: 0004-2749

DOI: 10.5935/0004-2749.20170032